Most home runs in an inning: Astros make MLB history with powerful outing vs. Red Sox

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The Astros put on a power display for the ages during the second inning of their game against the Red Sox at Fenway Park on Tuesday.

Houston smacked five homers during the inning of Boston starter Nathan Eovaldi. That allowed the Astros to jump out to a 9-1 lead and stunned the crowd on hand at Fenway.

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Yordan Alvarez got the party started with a 360-foot blast into the Green Monster. From there, Kyle Tucker, Jeremy Peña, Michael Brantley and Yuli Gurriel all followed suit. Tucker's was the longest of the bunch at 413 feet while Brantley's three-run jack resulted in the most runs.

Eovaldi, the Red Sox ace, was unable to get out of the inning. He became just the 123rd pitcher in MLB history to allow five or more homers in a single game.

But the Astros made even more history, as their string of long balls tied MLB's record for homers in a single inning.

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Most home runs hit in one inning in MLB history

The MLB record for team home runs in a single inning is five. The Astros tied that record on Tuesday night, and it marked the eighth time in MLB history that feat was achieved.

The eight, five-homer innings were achieved by seven different MLB teams. The only team to do it twice is the Giants, who did it while in New York in 1939 and San Francisco in 1961.

Below is the full list of teams to hit five homers in a single inning.

Year Team
1939 New York Giants
1949 Phillies
1961 Giants
1966 Twins
2006 Brewers
2017 Nationals
2020 Yankees
2022 Astros

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The Astros are one of just three teams on that list to hit all five homers off the same pitcher, Eovaldi. The Nationals were the first to do it against Tyler Blazek and the Brewers in 2017. Meanwhile, the Yankees hit five off Chase Anderson during the COVID-shortened 2020 MLB season.

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Jacob Camenker is a digital content producer for Sporting News. He began at Sporting News as a fantasy football intern and previously worked for NBC Sports Boston